Garcinia cambogia (Hydroxycitric Acid) as a Potential Antiobesity Agent

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Garcinia cambogia (hydroxycitric acid) as a potential antiobesity agent: a randomized controlled trial.

CONTEXT Hydroxycitric acid, the active ingredient in the herbal compound Garcinia cambogia, competitively inhibits the extramitochondrial enzyme adenosine triphosphate-citrate (pro-3S)-lyase. As a citrate cleavage enzyme that may play an essential role in de novo lipogenesis inhibition, G cambogia is claimed to lower body weight and reduce fat mass in humans. OBJECTIVE To evaluate the efficac...

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Garcinia (Garcinia cambogia), Hydroxycitric acid

1 of 5 12/11/07 3:10 PM Garcinia (Garcinia cambogia), Hydroxycitric acid Natural Standard Bottom Line Monograph, Copyright © 2007 (www.naturalstandard.com). Commercial distribution prohibited. This monograph is intended for informational purposes only, and should not be interpreted as specific medical advice. You should consult with a qualified healthcare provider before making decisions about ...

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The Garcinia Cambogia in Phytotreatment of Obesity:activities of the Hydroxycitric Acid

The objective of our work has been the identification in the bark of Garcinia cambogia (GC) of the HCA that has proven effective in blocking weight increase. The Hydroxycitric Acid (HCA) is a present alimentary acid in some varieties of tropical fruits, between which the Garcinia cambogia Desr. Its effect on the organism is that one to block to the activity of ATPcitrate lyase in charge of the ...

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Updates on Antiobesity Effect of Garcinia Origin (−)-HCA

Garcinia is a plant under the family of Clusiaceae that is commonly used as a flavouring agent. Various phytochemicals including flavonoids and organic acid have been identified in this plant. Among all types of organic acids, hydroxycitric acid or more specifically (-)-hydroxycitric acid has been identified as a potential supplement for weight management and as antiobesity agent. Various in vi...

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Effects of garcinia cambogia (Hydroxycitric Acid) on visceral fat accumulation: a double-blind, randomized, placebo-controlled trial.

BACKGROUND (-)-Hydroxycitric acid (HCA) is an active ingredient extracted from the rind of the Indian fruit Garcinia cambogia. It inhibits adenosine triphosphate citrate lyase and has been used in the treatment of obesity. OBJECTIVE The primary end point of this study was the effects of 12 weeks of G cambogia extract administration on visceral fat accumulation. The secondary end points were b...

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ژورنال

عنوان ژورنال: JAMA

سال: 1998

ISSN: 0098-7484

DOI: 10.1001/jama.280.18.1596